The AMYPAD Diagnostic and Patient Management Study (DPMS) selected and followed-up a memory clinic population suspected of possible Alzheimer’s disease (AD), focussing on those with subjective cognitive decline (SCD), mild cognitive impairment (MCI) and dementia where Alzheimer’s disease is in the differential diagnosis, to determine the usefulness of β-amyloid imaging with regards to diagnostic confidence, decision trees, change in diagnosis, and alterations between planned and actual patient management plans.