Dear friends and colleagues,

Hope this newsletter finds you well. We are back at work again after summer holidays and it’s hard to believe that our AMYPAD consortium is now in its last month of formal operation after six years of concerted efforts and collaboration. Recruitment on both AMYPAD studies is now completed and final data and images from sites are being collected and consolidated. We are proud to announce that in total AMYPAD has collected nearly 3,600 amyloid PET scans. Over 860 were from the Diagnostic and Prognostic Study (DPMS) with the remaining 2,700 coming from the Prognostic and Natural History Study (PNHS). This includes the collaborations with the other ten parent cohorts which have yielded an impressive 1,300 images to contribute to the PNHS body of images. The hard work to analyse all these scans is now ongoing as we move towards the close of the consortium.

AMYPAD also has just returned from the annual (but first face to face in 3 years) Alzheimer’s Association International Conference (AAIC), this year held in San Diego (US). We were fortunate to be awarded an online ‘Featured Research Session’ and had great feedback on both our technical and clinical presentations. Additionally, a number of posters were presented too. The utility of amyloid-PET remains of high interest particularly as we wait for the pivotal study outcomes of several anti-amyloid therapies to be presented at the next CTAD meeting in December.

Our final General Assembly is planned for the 22^nd and 23^rd of September in Amsterdam (Netherlands) and we have an exciting and wide-ranging agenda covering the analysis of both our studies as well as discussing future activities post-IMI funding period. One of the main points of interest too will be to explain our governance mechanisms for accessing the wealth of data that we have generated and how this will be maintained and made available going forwards.

From both Frederik and myself, we are extremely proud to have been associated with this high performing consortium and all the wonderful partners and collaborators we have made over the last six years.

In this issue, we present you the achievements of the past quarter, the AMYPAD latest papers and our participation in relevant events. In addition, you can also get to know three AMYPAD collaborators Laura Stankeviciute, Alle Meije Wink and Valentina Garibotto, who share some of their experiences with us. 

You can download the newsletter here.