The Alzheimer’s Association International Conference (AAIC) is the largest and most influential international meeting dedicated to advancing dementia science. Each year, AAIC convenes the world’s leading basic scientists, clinical researchers, early career investigators, clinicians and the care research community to share breaking research discoveries that will lead to methods of prevention and treatment and improvements in diagnosis for Alzheimer’s disease.

This year, the event will be held in Amsterdam (Netherlands) and online on 16-20 July, 2023. We are pleased that AMYPAD has the opportunity to hold a Featured Research Session. Featured Research Sessions (FRS) debut and discuss innovative and impactful research findings, drawing together multiple studies that share a common focus.
Moreover, our AMYPAD Featured Research Session got assigned a “Clinical Pearl Session”.

• AMYPAD Featured Research Session: “Towards clinical implementation of Centiloid quantification: Lessons learned from the AMYPAD consortium”
  Chairs: Christopher Buckley (GE Healthcare) and Juan Domingo Gispert (BBRC)
  Sunday, July 16th 9:15-10:30 am CET (Hall 2)
  

1. Mahnaz Shekari (BBRC): “Evaluating the sensitivity of Centiloid quantification to pipeline design and image harmonization“
2. Ariane Bollack (UCL): “A Centiloid cut-off to help predict true amyloid accumulation”
3. Lyduine E. Collij (VUmc): “Quantification supports visual assessment of challenging amyloid–PET images”
4. Lisa Quenon (UC Louvain): “Evaluating the global cortical Centiloid value for predicting functional decline“

In addition to the Featured Research Session, several AMYPAD posters will be presenting at the upcoming AAIC Conference:

• Melina Regy: “The association between abeta aggregation and age depends on APOE genotype: findings from the AMYPAD cohort”, Sunday 16th July to Wednesday 19th July
• Marianna Rizzo: “Prediction of longitudinal cortical amyloid deposition based on cerebrospinal fluid biomarkers for Alzheimer’s disease in cognitively unimpaired individuals: the role of APOE-ε4”, Sunday 16th July (P1-306)
• Philip Zeyen: “AMYPAD: Correlation of amyloid-PET results with anxiety and depressive symptoms in SCD+, MCI, and dementia patients”, Monday 17th July (P2-487)
• Leonard Pieperhoff: “Amyloid predicts longitudinal atrophy in non-demented individuals: Results from the AMYPAD Prognostic & Natural History study”, Monday 17th July (P2-918)
• Emma Luckett/Lyduine Collij: “Differential associations between regional amyloid PET and Alzheimer’s disease polygenic risk scores”, Tuesday 18th July (P3-003)
• Fiona Heeman: “Comparing parametric methods for longitudinal measurement of β-amyloid pathology with PET in elderly individuals”, Tuesday 18th July (P3-415)
• Luigi Lorenzini: “APOE-dependent and -independent polygenic pathways determining early AD pathological change in CSF and MRI”, Tuesday 18th July (P3-002)
• Sophie Mastenbroek: “Biological and methodological factors underlying a continuous amyloid CSF/PET imbalance model and its association with longitudinal cognition”, Wednesday July 19th (P4-334)
• David Vallez Garcia: “Amyloid-PET Centiloid quantification predicts cognitive functioning in a pre-dementia population: findings from AMYPAD PNHS”, Wednesday 19th July (P4-383).

Luigi Lorenzini will also be giving an oral presentation entitled “Vascular contribution to the preclinical AD pathological changes: insights from the EPAD cohort”.

We are very much looking forward to the conference and presenting our work! More information will be shared in due time.

For further information about this event, or to register for AAIC, click here.

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The Alzheimer’s Imaging Consortium (AIC), a preconference to AAIC, focusing on the frontiers of neuroimaging of Alzheimer’s and other dementia will be held on Saturday 15th July and will feature several AMYPAD presentations:

ORAL:

• Luigi Lorenzini: “APOE-dependent and -independent polygenic pathways determining early AD pathological change in CSF and MRI”, 13:46pm-13:54 (Hall2)

POSTERS:

• Luigi Lorenzini: “Vascular contribution to the preclinical AD pathological changes: insights from the EPAD cohort” (AIC-P-049)
• David Vallez Garcia: “Amyloid-PET Centiloid quantification predicts cognitive functioning in a pre-dementia population: findings from AMYPAD PNHS” (AIC-P-139)
• Fiona Heeman: “Comparing parametric methods for longitudinal measurement of b-amyloid pathology with PET in elderly individuals” (AIC-P-186)
• Ariane Bollack: “A Centiloid cut-off to predict true amyloid accumulation” (AIC-P-256)
• Sophie Mastenbroek: “Biological and methodological factors underlying a continuous amyloid CSF/PET imbalance model and its association with longitudinal cognition” (AIC-P-048)
• Mahnaz Shekari: “Evaluating the sensitivity of Centiloid quantification to pipeline design and image harmonization” (AIC-P-255)