A new paper titled “Longitudinal amyloid PET changes by cerebrospinal fluid amyloid and tau profiles in individuals with normal cognition: Role of APOE ε4” has been published in the journal of Alzheimer’s disease. The objective of this study was toinvestigate the associations of Alzheimer’s disease cerebrospinal fluid (CSF) biomarkers with early longitudinal amyloid deposition on positron emission tomography (PET), and the impact of APOE ε4 carriership. In this work, authors selected cognitively unimpaired participants with baseline data on CSF amyloid and p-tau181, APOE ε4 carriership, and ≥ 2 consecutive amyloid PET assessments from the AMYPAD-PNHS cohort.

You can download the paper here: https://doi.org/10.1177/138728772614530

Congratulations to Marianna Rizzo and Julie E. Oomens.