The Alzheimer’s Association International Conference (AAIC) is the largest and most influential international meeting dedicated to advancing dementia science. Each year, AAIC convenes the world’s leading basic scientists, clinical researchers, early career investigators, clinicians and the care research community to share breaking research discoveries that will lead to methods of prevention and treatment and improvements in diagnosis for Alzheimer’s disease.

This year, the event will be held in Amsterdam (Netherlands) and online on 16-20 July, 2023. We are pleased that AMYPAD has the opportunity to hold a Featured Research Session. Featured Research Sessions (FRS) debut and discuss innovative and impactful research findings, drawing together multiple studies that share a common focus.
Moreover, our AMYPAD Featured Research Session got assigned a “clinical pearl session”.

• AMYPAD Featured Research Session: “Towards clinical implementation of Centiloid quantification: Lessons learned from the AMYPAD consortium”
  Chairs: Christopher Buckley (GE Healthcare) and Juan Domingo Gispert (BBRC)
  Sunday, July 16th 9:15-10:30 am CET
  

1. Mahnaz Shekari (BBRC): “Evaluating the sensitivity of Centiloid quantification to pipeline design and image harmonization“
2. Ariane Bollack (UCL): “Longitudinal Centiloid quantification: predicting true accumulators“
3. Lyduine E. Collij (VUmc): “Quantification supports visual assessment of challenging amyloid–PET images”
4. Lisa Quenon (UC Louvain): “Evaluating the global cortical Centiloid value for predicting functional decline“

In addition to the Featured Research Session, several AMYPAD posters will be presenting at the upcoming AAIC Conference:

• Marianna Rizzo: “Prediction of longitudinal cortical amyloid deposition based on cerebrospinal fluid biomarkers for Alzheimer’s disease in cognitively unimpaired individuals: the role of APOE-ε4”
• Fiona Heeman: “Comparing parametric methods for longitudinal measurement of β-amyloid pathology with PET in elderly individuals”
• Sophie Mastenbroek: “Biological and methodological factors underlying a continuous amyloid CSF/PET imbalance model and its association with longitudinal cognition”
• Luigi Lorenzini: “APOE-dependent and -independent polygenic pathways determining early AD pathological change in CSF and MRI”
• Melina Regy: “The association between abeta aggregation and age depends on APOE genotype: findings from the AMYPAD cohort”
• David Vallez Garcia: “Amyloid-PET Centiloid quantification predicts cognitive functioning in a pre-dementia population: findings from AMYPAD PNHS”
• Philip Zeyen: “AMYPAD: Correlation of amyloid-PET results with anxiety and depressive symptoms in SCD+, MCI, and dementia patients”
• Emma Luckett/Lyduine Collij: “Differential associations between regional amyloid PET and Alzheimer’s disease polygenic risk scores”

Luigi Lorenzini will also be giving an oral presentation entitled “Vascular contribution to the preclinical AD pathological changes: insights from the EPAD cohort”.

We are very much looking forward to the conference and presenting our work! More information will be shared in due time.

For further information about this event, or to register for AAIC, click here.

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The Alzheimer’s Imaging Consortium (AIC), a preconference to AAIC, focusing on the frontiers of neuroimaging of Alzheimer’s and other dementia will be held on Saturday 15th July and will feature several AMYPAD presentations:

ORAL:

• Luigi Lorenzini: “APOE-dependent and -independent polygenic pathways determining early AD pathological change in CSF and MRI”

POSTERS:

• Luigi Lorenzini: “Vascular contribution to the preclinical AD pathological changes: insights from the EPAD cohort”
• David Vallez Garcia: “Amyloid-PET Centiloid quantification predicts cognitive functioning in a pre-dementia population: findings from AMYPAD PNHS”
• Ariane Bollack: “Comparing parametric methods for longitudinal measurement of b-amyloid pathology with PET in elderly individuals”
• Ariane Bollack: “A Centiloid cut-off to predict true amyloid accumulation”
• Sophie Mastenbroek: “Biological and methodological factors underlying a continuous amyloid CSF/PET imbalance model and its association with longitudinal cognition”
• Mahnaz Shekari: “Evaluating the sensitivity of Centiloid quantification to pipeline design and image harmonization”