The AMYPAD Diagnostic and Patient Management Study (DPMS) has selected and is following-up a memory clinic population suspected of possible Alzheimer's disease (AD), focussing on those with subjective cognitive decline (SCD), mild cognitive impairment (MCI) and dementia where Alzheimer's disease is in the differential diagnosis, to determine the usefulness of β-amyloid imaging with regards to diagnostic confidence, decision trees, change in diagnosis, and alterations between planned and actual patient management plans.
The DPMS study succeeded in recruiting 844 of the planned 900 participants when recruitment was formally ended on 30 October 2020. A total of 245 people with SCD, 342 with MCI and 258 with dementia had been enrolled. The different sites completed all remaining visits and scans during the month of June 2021. The data cleaning process has been initiated.